Endocrine Abstracts

Introduction: Prolonged therapy with high-dose corticosteroids (≥ 7.5 mg Prednisolone or 1–1.5 mg Dexamethasone daily) can result in adrenal atrophy and hypofunction. Abrupt withdrawal of corticosteroids after prolonged use can lead to adrenal insufficiency, corticosteroid withdrawal symptoms or a relapse of the initial disease. There are several in-house protocols for safe corticosteroid dose tapering but a national protocol is required.Our p...

Introduction: Hyponatraemia following surgery is usually due to a mismatch between fluid input and output peri- and post-operatively. Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is another important cause of hyponatraemia, commonest cause being medications, and intrathoracic and intracranial infections and neoplasia. SIADH has been reported to occur after pituitary surgery but rarely after other types of surgery. We present a severe case of SIADH-related h...